Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.36 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10318931 | 0.81 | NISCH (0.37) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10320215 | 0.81 | NISCH (0.37) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10319831 | 0.80 | NISCH (0.36) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10317793 | 0.80 | NISCH (0.36) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10319712 | 0.78 | HSD11B1 (0.35) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10319118 | 0.78 | SMN1; SMN2 (0.36) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10319457 | 0.78 | NISCH (0.35) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10320586 | 0.78 | NISCH (0.35) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10317942 | 0.77 | ALDH1A1 (0.36) | NISCHHTR1DCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10318862 | 0.77 | SMN1; SMN2 (0.36) | NISCHHTR1DCA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133928-A1 | TRIMERIZATION CATALYST AND METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012133936-A1 | CATALYST FOR PRODUCING ETHYLENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | WO | disclosed |