Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819156 | 0.93 | PGR (0.39) | PGRCPT2CPT1ACPT1BGCK | |
| SCHEMBL12818327 | 0.87 | CYP11B1 (0.38) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL12818990 | 0.85 | CYP2C9 (0.38) | PGRCPT1ACPT1BGCKALDH1A1 | |
| SCHEMBL12818019 | 0.85 | PKM (0.42) | CPT2CPT1ACPT1BLMNAALDH1A1 | |
| SCHEMBL12818273 | 0.84 | PGR (0.36) | PGRGCK | |
| SCHEMBL12818376 | 0.84 | PGR (0.38) | PGRGCKLMNAALDH1A1PKM | |
| SCHEMBL12818379 | 0.84 | PGR (0.38) | PGRCPT2CPT1ACPT1BGCK | |
| SCHEMBL12817683 | 0.83 | CPT2 (0.34) | PGRCPT2CPT1ACPT1BCNR1 | |
| SCHEMBL12817920 | 0.81 | CYP11B1 (0.40) | PGRCPT2CPT1ACPT1BCNR1 | |
| SCHEMBL12817890 | 0.80 | HSPD1 (0.40) | PGRCPT2CPT1ACPT1BGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |