Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17516010 | 0.87 | S1PR1 (0.42) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL16166497 | 0.86 | MAPT (0.43) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL18902665 | 0.86 | EPHX2 (0.41) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL12816502 | 0.80 | LMNA (0.32) | MAPTALDH1A1LMNAGAA | |
| SCHEMBL16422050 | 0.80 | MAPT (0.39) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL12816693 | 0.78 | — | — | |
| SCHEMBL525875 | 0.77 | MAPT (0.46) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL525874 | 0.77 | CTSL (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL2548785 | 0.77 | SCN1A (0.40) | MAPTNPC1MAPK1RAB9AMEN1 | |
| SCHEMBL12817742 | 0.72 | MAPT (0.47) | MAPTNPC1MAPK1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131710-A2 | NOVEL PROCESS FOR THE SYNTHESIS OF INDOLINE DERIVATIVES | PANACEA BIOTEC LTD (IN) | 2012-10-04 | — | — | WO | claimed |
| WO-2012131710-A2 | NOVEL PROCESS FOR THE SYNTHESIS OF INDOLINE DERIVATIVES | PANACEA BIOTEC LTD (IN) | 2012-10-04 | — | — | WO | disclosed |