Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505326 | 0.85 | MAPT (0.38) | MAPTNPC1RAB9AMAPK1NOTUM | |
| SCHEMBL526254 | 0.84 | NOTUM (0.38) | MAPTNPC1RAB9AMAPK1NOTUM | |
| SCHEMBL2548785 | 0.80 | SCN1A (0.40) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL525874 | 0.79 | CTSL (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL526977 | 0.78 | NOTUM (0.67) | MAPTNPC1RAB9AMAPK1NOTUM | |
| SCHEMBL16422050 | 0.78 | MAPT (0.39) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL18902665 | 0.78 | EPHX2 (0.41) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL12817652 | 0.77 | MAPT (0.39) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL526097 | 0.77 | NOTUM (0.49) | MAPTNPC1RAB9AMAPK1NOTUM | |
| SCHEMBL17516010 | 0.76 | S1PR1 (0.42) | MAPTNPC1RAB9AMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014186-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN AND ITS NOVEL INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |