Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 9/20 | 0.39 |
| ▸ | EDNRA | P25101 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517722 | 0.78 | CYP1A2 (0.50) | TSHRPOLBPTPRARAB9ANPC1 | |
| SCHEMBL5521719 | 0.78 | LMNA (0.44) | TSHRPOLBPTPRARAB9ANPC1 | |
| SCHEMBL7037791 | 0.75 | ATM (0.47) | EDNRBEDNRARAB9ANPC1ALDH1A1 | |
| SCHEMBL10337588 | 0.75 | LMNA (0.41) | TSHRPOLBPTPRARAB9ANPC1 | |
| SCHEMBL10524022 | 0.75 | LMNA (0.41) | TSHRPOLBPTPRARAB9ANPC1 | |
| SCHEMBL5515471 | 0.74 | ALDH1A1 (0.55) | TSHRPTPRARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11911978 | 0.74 | CYP1A2 (0.38) | TSHRPOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4611560 | 0.73 | PPARA (0.43) | POLBPTPRARAB9ANPC1SMN1; SMN2 | |
| Acetic Acid SCHEMBL28009762 | 0.73 | PDE4A (0.48) | TSHRRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21881598 | 0.73 | PPARA (0.43) | POLBPTPRARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722662-B2 | Heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20120088748-A1 | HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088748-A1 | HETEROCYCLIC COMPOUNDS | SLC6A2, MAOB, MAOA | TSHR 757/4885EDNRB 450/4885EDNRA 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.