Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1281730 | 0.99 | HSP90AB1 (0.32) | HSP90AB1GRM2LMNAMAPK14MAPK1 | |
| SCHEMBL1282161 | 0.96 | HSP90AB1 (0.33) | HSP90AB1GRM2LMNAMAPK14MAPK1 | |
| SCHEMBL1282307 | 0.90 | S1PR4 (0.35) | LMNACYP3A4CYP2C19LTB4RLTB4R2 | |
| SCHEMBL1282368 | 0.90 | PPARA (0.37) | LMNAALDH1A1POLBS1PR4 | |
| SCHEMBL1282353 | 0.90 | MAPK1 (0.41) | MAPK1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL1281725 | 0.89 | S1PR4 (0.36) | LMNAMAPK1CYP3A4CYP2C19LTB4R | |
| SCHEMBL1282273 | 0.89 | PPARA (0.37) | LMNAALDH1A1POLBS1PR4 | |
| SCHEMBL1282133 | 0.89 | MAPK1 (0.42) | MAPK1CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL1282264 | 0.86 | S1PR4 (0.36) | LMNAMAPK1CYP3A4CYP2C19MEN1 | |
| SCHEMBL1282240 | 0.86 | DHFR (0.38) | LMNACYP3A4ALDH1A1POLBS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443098-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146112-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | HSP90AB1 1662/4885GRM2 3205/4885LMNA 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.