Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1281725 | 0.99 | S1PR4 (0.36) | S1PR4ALDH1A1CYP3A4HTR1AHTR7 | |
| SCHEMBL1282264 | 0.96 | S1PR4 (0.36) | S1PR4ALDH1A1CYP3A4HTR1AHTR7 | |
| SCHEMBL2122104 | 0.93 | DRD2 (0.33) | S1PR4ALDH1A1CYP3A4HTR1AHTR7 | |
| SCHEMBL1281978 | 0.90 | HSP90AB1 (0.32) | S1PR4ALDH1A1CYP3A4LTB4RLTB4R2 | |
| SCHEMBL1282510 | 0.90 | HPGD (0.39) | S1PR4ALDH1A1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL1282429 | 0.89 | HPGD (0.40) | S1PR4ALDH1A1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL1281730 | 0.89 | HSP90AB1 (0.32) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL1282368 | 0.86 | PPARA (0.37) | S1PR4ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL1282197 | 0.86 | HPGD (0.41) | S1PR4ALDH1A1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL1282161 | 0.86 | HSP90AB1 (0.33) | ALDH1A1CYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | S1PR4 2670/4885ALDH1A1 1943/4885CYP3A4 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.