Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303350 | 0.89 | P2RY1 (0.49) | P2RY1MAPTCARM1PRMT6KDM4E | |
| SCHEMBL12303348 | 0.88 | P2RY1 (0.50) | P2RY1MAPTCARM1PRMT6KDM4E | |
| SCHEMBL12303836 | 0.76 | KDM4E (0.48) | P2RY1CARM1KDM4EKCNH2MEN1 | |
| SCHEMBL11922609 | 0.69 | P2RY1 (0.46) | P2RY1MAPTCARM1PRMT6ROCK2 | |
| SCHEMBL12303356 | 0.69 | KCNH2 (0.67) | P2RY1CARM1PRMT6KCNH2CYP2C19 | |
| SCHEMBL11991497 | 0.68 | P2RY1 (0.43) | P2RY1MAPTCARM1PRMT6ROCK2 | |
| SCHEMBL12303378 | 0.68 | CYP2C19 (0.43) | P2RY1CARM1PRMT6KDM4EMEN1 | |
| SCHEMBL13044770 | 0.68 | CFTR (0.53) | P2RY1MAPTKDM4EROCK2 | |
| SCHEMBL12819937 | 0.66 | DRD1 (0.43) | P2RY1MAPTKCNH2 | |
| SCHEMBL12818227 | 0.66 | KCNH2 (0.63) | P2RY1MAPTCARM1PRMT6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |