Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CD38 | P28907 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303350 | 0.92 | P2RY1 (0.49) | P2RY1CARM1PRMT6RPS6KB1AURKA | |
| SCHEMBL12819968 | 0.88 | P2RY1 (0.45) | P2RY1CARM1PRMT6RPS6KB1AURKA | |
| SCHEMBL12303836 | 0.87 | KDM4E (0.48) | P2RY1CARM1RPS6KB1AURKAAURKB | |
| SCHEMBL12303376 | 0.77 | RPS6KB1 (0.45) | P2RY1CARM1PRMT6RPS6KB1AURKA | |
| SCHEMBL13044770 | 0.72 | CFTR (0.53) | P2RY1ROCK2MAPTKDM4E | |
| SCHEMBL11922609 | 0.71 | P2RY1 (0.46) | P2RY1CARM1PRMT6ROCK2MAPT | |
| SCHEMBL12303356 | 0.71 | KCNH2 (0.67) | P2RY1CARM1PRMT6KCNH2CYP2C19 | |
| SCHEMBL11991497 | 0.70 | P2RY1 (0.43) | P2RY1CARM1PRMT6ROCK2MAPT | |
| SCHEMBL12303615 | 0.70 | KCNH2 (0.51) | P2RY1RPS6KB1AURKAROCK2CD38 | |
| SCHEMBL12303378 | 0.70 | CYP2C19 (0.43) | P2RY1CARM1PRMT6RPS6KB1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | P2RY1 1687/4885CARM1 3715/4885PRMT6 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.