SCHEMBL12820201

SCHEMBL12820201

C=C(N)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.58
KDM4E B2RXH2 6/20 0.58
ALDH1A1 P00352 5/20 0.58
HSD17B10 Q99714 5/20 0.58
TSHR P16473 3/20 0.58
MAPT P10636 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.48
CA1 P00915 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA14 Q9ULX7 2/20 0.48
HMGB1 P09429 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
LMNA P02545 4/20 0.45
ALOX15 P16050 4/20 0.45
NPC1 O15118 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12018275 0.83 ALDH1A1 (0.42) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL4801020 0.78 HPGD (0.52) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL1628732 0.77 KDM4E (0.61) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL3190837 0.76 HPGD (0.56) HPGDKDM4EALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL2132350 0.75 KDM4E (0.91) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL12856009 0.74 HPGD (0.48) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL29349932 0.74 KMT2A (0.56) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL7027832 0.74 HPGD (0.48) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL12819640 0.74 HPGD (0.48) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL7175383 0.74 ALDH1A1 (0.48) HPGDKDM4EALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
EP-2527399-B1 POLYESTER RESIN COMPOSITION FUJIFILM CORP (JP) 2016-06-01 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
EP-2301995-A1 Polycarbonate resin composition containing triazine compound and molded article using the same Fujifilm Corporation (JP) 2011-03-30 EP disclosed