Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841260 | 1.00 | TTR (0.42) | TTRMAOAMAOBHTR2AHTR2C | |
| SCHEMBL16957954 | 0.83 | F2RL1 (0.40) | NFE2L2F2RL1 | |
| SCHEMBL5422596 | 0.83 | MAOA (0.37) | TTRMAOAMAOBHTR2AHTR2C | |
| SCHEMBL14604968 | 0.79 | MAOA (0.42) | TTRMAOAMAOBHTR2AHTR2C | |
| SCHEMBL3437039 | 0.78 | TDP1 (0.56) | TTRMAOB | |
| SCHEMBL257321 | 0.78 | NFE2L2 (0.61) | HTR2AHTR2CKCNH2NFE2L2F2RL1 | |
| SCHEMBL13891146 | 0.78 | NFE2L2 (0.61) | HTR2AHTR2CKCNH2NFE2L2F2RL1 | |
| SCHEMBL10322591 | 0.78 | TDP1 (0.56) | TTRMAOB | |
| SCHEMBL7651798 | 0.78 | NFE2L2 (0.61) | HTR2AHTR2CKCNH2NFE2L2F2RL1 | |
| SCHEMBL23347609 | 0.77 | GABRA1 (0.49) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943900-B | Isoxazoline derivatives and their use in agriculture | 宁夏苏融达化工有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111943900-A | Isoxazoline derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2020-11-17 | — | — | CN | disclosed |
| WO-2011038163-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2011-03-31 | — | — | WO | disclosed |