Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 9/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12771027 | 0.91 | HDAC4 (0.41) | HDAC4HDAC1ACEPRCPF2 | |
| SCHEMBL12820514 | 0.90 | HDAC4 (0.41) | HDAC4HDAC1ACEPRCPF2 | |
| SCHEMBL8225015 | 0.85 | ACE (0.49) | HDAC4HDAC1ACERENF2 | |
| SCHEMBL2812234 | 0.81 | HDAC4 (0.51) | HDAC4HDAC1LMNAMAPT | |
| SCHEMBL1445009 | 0.81 | HDAC4 (0.51) | HDAC4HDAC1LMNAMAPT | |
| SCHEMBL8222822 | 0.81 | ACE (0.39) | ACERENPRCPKDM4EF2 | |
| SCHEMBL4257798 | 0.80 | HDAC4 (0.49) | HDAC4HDAC1LMNA | |
| SCHEMBL4257792 | 0.80 | HDAC4 (0.49) | HDAC4HDAC1LMNA | |
| SCHEMBL8281588 | 0.80 | HDAC4 (0.40) | HDAC4HDAC1 | |
| SCHEMBL8293879 | 0.80 | HDAC4 (0.40) | HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034518-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2011-03-24 | — | — | WO | disclosed |