Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12959076 | 1.00 | PNP (0.56) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL40998 | 1.00 | PNP (0.56) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL30326363 | 0.99 | PNP (0.55) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL30867121 | 0.92 | PNP (0.47) | PNPTLR7MEN1KMT2ACYP3A4 | |
| Cytidine SCHEMBL28233906 | 0.91 | LMNA (0.65) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL19552748 | 0.91 | PNP (0.48) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL19183038 | 0.91 | PNP (0.45) | PNPTLR7MEN1KMT2AHINT1 | |
| Triphosphate SCHEMBL31158164 | 0.90 | PNP (0.47) | PNPTLR7MEN1KMT2ALMNA | |
| SCHEMBL29565496 | 0.89 | PNP (0.45) | PNPTLR7MEN1KMT2ACYP3A4 | |
| SCHEMBL29714505 | 0.89 | PNP (0.47) | PNPTLR7MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035009-A1 | HETEROCYCLIC GTP CYCLOHYDROLASE 1 INHIBITORS FOR THE TREATMENT OF PAIN | HERCULES TECHNOLOGY MANAGEMENT CO V, INC. (US) | 2011-03-24 | — | — | WO | disclosed |