SCHEMBL40998

SCHEMBL40998

C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 1/20 0.56
▸ TLR7 Q9NYK1 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ CYP3A4 P08684 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ LMNA P02545 2/20 0.47
▸ MTOR P42345 2/20 0.47
▸ THRB P10828 1/20 0.47
▸ MDM2 Q00987 1/20 0.47
▸ NCOA1 Q15788 1/20 0.47
▸ NCOA3 Q9Y6Q9 1/20 0.47
▸ GMNN O75496 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ NFKB1 P19838 1/20 0.47
▸ DNMT1 P26358 1/20 0.47
▸ THPO P40225 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12959076 1.00 PNP (0.56) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL12820927 1.00 PNP (0.56) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL30326363 0.99 PNP (0.55) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL30867121 0.92 PNP (0.47) PNPTLR7MEN1KMT2ACYP3A4
Cytidine SCHEMBL28233906 0.91 LMNA (0.65) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL19552748 0.91 PNP (0.48) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL19183038 0.91 PNP (0.45) PNPTLR7MEN1KMT2AHINT1
Triphosphate SCHEMBL31158164 0.90 PNP (0.47) PNPTLR7MEN1KMT2ALMNA
SCHEMBL29565496 0.89 PNP (0.45) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL29714505 0.89 PNP (0.47) PNPTLR7MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15313 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 — — US claimed
CN-122095092-A Inhibitor for inhibiting inhibin Beta E gene expression and application thereof — 2026-05-26 — — CN claimed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 — — CN claimed
EP-4739794-A1 METHODS, COMPOSITONS, AND SYSTEMS FOR ANALYTE DETECTION Stellaromics, Inc. (US) 2026-05-13 — — EP claimed
EP-4739343-A2 CIRCULAR RNA VACCINES FOR SEASONAL FLU AND METHODS OF USES Shanghai Circode Biomed Co., Ltd (CN) 2026-05-13 — — EP claimed
WO-2026090312-A1 MODULAR RNA MODIFICATION MODEL TRAINING FRAMEWORK NORTHEASTERN UNIVERSITY (US) 2026-04-30 — — WO claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 — — EP claimed
EP-4689071-A2 MRNA THERAPEUTICS FOR OOCYTE MATURATION Eastern Virginia Medical School (US) 2026-02-11 — — EP claimed
EP-4684016-A2 METHODS AND MATERIALS FOR TREATING CANCER The Regents of the University of California (US) 2026-01-28 — — EP claimed
US-20260014185-A1 Delivery of RNA to Different Cell Types GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2026-01-15 — — US claimed
EP-0842286-A2 COMPOSITIONS AND METHOD FOR MODULATION OF GENE EXPRESSION IN PLANTS RIBOZYME PHARMACEUTICALS, INC. (US) 1998-05-20 — — EP claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 — — EP claimed
WO-1997024455-A2 METHODS AND COMPOSITIONS FOR FULL-LENGTH cDNA CLONING CLONTECH LABORATORIES, INC. (US) 1997-07-10 — — WO claimed
WO-1997010328-A2 COMPOSITIONS AND METHOD FOR MODULATION OF GENE EXPRESSION IN PLANTS RIBOZYME PHARMACEUTICALS, INC. (US) 1997-03-20 — — WO claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 — — WO claimed
WO-1994006811-A1 SILOXY OLIGONUCLEOTIDE ANALOGS INTEGRATED DNA TECHNOLOGIES, INC. (US) 1994-03-31 — — WO claimed
EP-0531447-A4 COMPOSITIONS AND METHODS FOR MODULATING RNA ACTIVITY THROUGH MODIFICATION OF THE 5' CAP STRUCTURE OF RNA — 1993-08-11 — — EP claimed
EP-0531447-A1 COMPOSITIONS AND METHODS FOR MODULATING RNA ACTIVITY THROUGH MODIFICATION OF THE 5' CAP STRUCTURE OF RNA ISIS PHARMACEUTICALS, INC. (US) 1993-03-17 — — EP claimed
US-5075225-A PROCESS FOR THE ENZYMATIC SYNTHESIS OF NUCLEOSIDES THE TEXAS A&M UNIVERSITY SYSTEM (US) 1991-12-24 — — US claimed
WO-1991017755-A1 COMPOSITIONS AND METHODS FOR MODULATING RNA ACTIVITY THROUGH MODIFICATION OF THE 5' CAP STRUCTURE OF RNA ISIS PHARMACEUTICALS, INC. (US) 1991-11-28 — — WO claimed
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