Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282118 | 0.99 | ALDH1A1 (0.40) | ALDH1A1CYP3A4PPARACPT1AHRH3 | |
| SCHEMBL1283733 | 0.95 | PPARA (0.41) | ALDH1A1CYP3A4PPARAFDPS | |
| SCHEMBL1281563 | 0.91 | PPARA (0.36) | ALDH1A1PPARA | |
| SCHEMBL1282110 | 0.90 | HTT (0.36) | ALDH1A1HRH3FDPS | |
| SCHEMBL1282566 | 0.90 | HDAC1 (0.38) | PPARAFDPS | |
| SCHEMBL1281900 | 0.89 | USP2 (0.36) | ALDH1A1PPARAHRH3FDPS | |
| SCHEMBL1282635 | 0.88 | KCNA3 (0.38) | PPARAFDPS | |
| SCHEMBL1281799 | 0.88 | HRH3 (0.40) | HRH3 | |
| SCHEMBL1283394 | 0.87 | HRH3 (0.39) | HRH3 | |
| SCHEMBL2122104 | 0.86 | DRD2 (0.33) | ALDH1A1CYP3A4PPARACPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443098-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146112-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | ALDH1A1 1943/4885CYP3A4 19/4885PPARA 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.