Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424865 | 0.86 | POLB (0.76) | POLBLMNAALDH1A1GAAKMT2A | |
| SCHEMBL29193980 | 0.83 | LMNA (0.45) | POLBLMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10845357 | 0.83 | MAPT (0.47) | POLBLMNAALDH1A1GAAKMT2A | |
| SCHEMBL15145823 | 0.82 | L3MBTL1 (0.51) | POLBLMNAALDH1A1KMT2AHPGD | |
| SCHEMBL3173666 | 0.82 | POLB (0.44) | POLBLMNAALDH1A1GAAKMT2A | |
| SCHEMBL14220634 | 0.80 | CYP2C19 (0.54) | POLBALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL28195151 | 0.80 | LMNA (0.45) | POLBLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15669430 | 0.80 | CTSL (0.43) | POLBLMNAALDH1A1GAAKMT2A | |
| SCHEMBL12321485 | 0.80 | LMNA (0.53) | POLBLMNAGAAKMT2AMEN1 | |
| SCHEMBL20380317 | 0.79 | LMNA (0.59) | POLBLMNAALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130915-A1 | SPIROALKENE CARBOXAMIDE DERIVATIVES AND THEIR USE AS CHEMOKINE RECEPTOR MODULATORS | ARES TRADING S.A. (CH) | 2012-10-04 | — | — | WO | disclosed |