Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | F12 | P00748 | 1/20 | 0.58 |
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38341 | 1.00 | BLM (0.58) | BLMRECQLTSHRPOLBMAPT | |
| SCHEMBL1766180 | 1.00 | BLM (0.58) | BLMRECQLTSHRPOLBMAPT | |
| SCHEMBL1774314 | 0.97 | BLM (0.55) | BLMRECQLTSHRPOLBMAPT | |
| Hydrochloric Acid SCHEMBL4620960 | 0.97 | BLM (0.60) | BLMRECQLTSHRPOLBMAPT | |
| SCHEMBL30465109 | 0.97 | BLM (0.55) | BLMRECQLTSHRPOLBMAPT | |
| SCHEMBL11303275 | 0.88 | BLM (0.48) | BLMRECQLTSHRPOLBMAPT | |
| Dimethylamine SCHEMBL2949614 | 0.88 | TSHR (0.48) | BLMRECQLTSHRPOLBMAPT | |
| SCHEMBL2143138 | 0.87 | TSHR (0.52) | BLMRECQLTSHRPOLBMAPT | |
| Sulfuric Acid SCHEMBL8015543 | 0.86 | MAPT (0.52) | BLMRECQLTSHRPOLBMAPT | |
| Sulfuric Acid SCHEMBL7009472 | 0.86 | MAPT (0.52) | BLMRECQLTSHRPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251071-A1 | METHOD TO MAKE SMALL-MOLECULE MURINE DOUBLE MINUTE 2 PROTEIN (MDM2)-DEGRADING COMPOUNDS, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2022-08-11 | — | — | US | disclosed |
| WO-2020232115-A1 | BIFUNCTIONAL NUTLIN-LENALIDOMIDE DERIVATIVES ((4,5-DIHYDRO-1H-IMIDAZOLE-1-CARBONYL)PIPERAZIN-1-YL-[LINKER]-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES) AS MDM2 DEGRADERS AND MDM2-P53 INHIBITORS FOR USE IN CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-11-19 | — | — | WO | disclosed |
| EP-2718978-B1 | ORGANIC ELECTRONIC DEVICE | NOVALED GMBH (DE) | 2018-05-16 | — | — | EP | disclosed |
| EP-2776387-B1 | TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION | UNIV EMORY (US) | 2017-02-01 | — | — | EP | disclosed |
| US-9142781-B2 | Compound for organic electronic device | NOVALED AG (DE) | 2015-09-22 | — | — | US | disclosed |
| US-8889863-B2 | Stereoselective methods, catalysts and intermediates for the synthesis of (−)-Nutlin-3 and related compounds | VANDERBILT UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140174537-A1 | Compound for Organic Electronic Device | NOVALED AG (DE) | 2014-06-26 | — | — | US | disclosed |
| US-8329903-B2 | Light-emitting element including organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329903-B2 | Light-emitting element including organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120123117-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-05-17 | — | — | US | disclosed |
| US-20120123117-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-05-17 | — | — | US | disclosed |
| US-20120088915-A1 | STEREOSELECTIVE METHODS, CATALYSTS AND INTERMEDIATES FOR THE SYNTHESIS OF (-)-NUTLIN-3 AND RELATED COMPOUNDS | VANDERBILT UNIVERSITY | 2012-04-12 | — | — | US | disclosed |
| US-8101755-B2 | Organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8101755-B2 | Organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-7850992-B2 | Cucurbituril-containing gel and method of preparing the same | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2010-12-14 | — | — | US | disclosed |
| US-20100105902-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-04-29 | — | — | US | disclosed |
| US-20100105902-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-04-29 | — | — | US | disclosed |
| US-20070154553-A1 | CUCURBITURIL-CONTAINING GEL AND METHOD OF PREPARING THE SAME | POSTECH FOUNDATION (KR) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105902-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | CRY1, CRY2, LAGE3 | BLM 1244/4885RECQL 819/4885TSHR 3199/4885 |
| US-20120088915-A1 | STEREOSELECTIVE METHODS, CATALYSTS AND INTERMEDIATES FOR THE SYNTHESIS OF (-)-NUTLIN-3 AND RELATED COMPOUNDS | NUTF2, MDM2, CIAPIN1 | BLM 1434/4885RECQL 1911/4885TSHR 4558/4885 |
| US-20120123117-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | CRY1, CRY2, LAGE3 | BLM 1244/4885RECQL 819/4885TSHR 3199/4885 |
| US-20070154553-A1 | CUCURBITURIL-CONTAINING GEL AND METHOD OF PREPARING THE SAME | CCNA1, CBX6, CCNL2 | BLM 1396/4885RECQL 696/4885TSHR 4741/4885 |
| US-20220251071-A1 | METHOD TO MAKE SMALL-MOLECULE MURINE DOUBLE MINUTE 2 PROTEIN (MDM2)-DEGRADING COMPOUNDS, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MDM2, TP53, MYCBP2 | BLM 984/4885RECQL 654/4885TSHR 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.