Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463305 | 0.83 | PLAU (0.32) | — | |
| SCHEMBL16923685 | 0.78 | TPMT (0.38) | TPMTGSK3BCA1CA2SLC22A2 | |
| SCHEMBL12824214 | 0.70 | — | — | |
| SCHEMBL12824210 | 0.68 | APP (0.33) | — | |
| SCHEMBL24934144 | 0.66 | MASP2 (0.35) | — | |
| SCHEMBL14896662 | 0.65 | MASP2 (0.39) | — | |
| SCHEMBL3303670 | 0.64 | IDO1 (0.42) | TPMTGSK3BCA1CA2IDO1 | |
| SCHEMBL22175238 | 0.63 | ESR1 (0.40) | CA1CA2 | |
| SCHEMBL22174797 | 0.62 | CYP19A1 (0.38) | SLC22A2SLC22A1 | |
| SCHEMBL22171329 | 0.62 | MASP2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |