Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24213539 | 0.80 | PLAU (0.44) | APP | |
| SCHEMBL18962609 | 0.78 | LMNA (0.45) | CA1CA2SLC22A2SLC22A1SLC22A3 | |
| SCHEMBL20644765 | 0.78 | CES2 (0.39) | CA1CA2SLC22A2SLC22A1SLC22A3 | |
| SCHEMBL24196737 | 0.78 | IRAK4 (0.30) | IRAK4 | |
| SCHEMBL14538523 | 0.78 | ALDH1A1 (0.40) | SLC22A2SLC22A1SLC22A3 | |
| SCHEMBL12824216 | 0.78 | TPMT (0.34) | TPMTCA1CA2SLC22A2SLC22A1 | |
| SCHEMBL15850351 | 0.77 | F2 (0.42) | — | |
| SCHEMBL22084095 | 0.75 | ALDH1A1 (0.47) | — | |
| SCHEMBL24690353 | 0.74 | HTT (0.47) | — | |
| SCHEMBL13439334 | 0.74 | NQO2 (0.38) | SLC22A2SLC22A1SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015107053-A1 | N-PHENYL-LACTAM DERIVATIVES CAPABLE OF STIMULATING NEUROGENESIS AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-07-23 | — | — | WO | disclosed |