Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257519 | 0.87 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL1257502 | 0.84 | ACHE (0.56) | IKBKBHCRTR1HCRTR2OPRK1 | |
| SCHEMBL12824668 | 0.82 | CHRNB2 (0.48) | CHRNB2CHRNA4KAT2BCHRNA7CHRNB1 | |
| SCHEMBL22768021 | 0.81 | HCRTR1 (0.49) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL2267304 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4KAT2BCHRNA7CHRNB4 | |
| SCHEMBL2267302 | 0.79 | CHRNB2 (0.50) | CHRNB2CHRNA4KAT2BCHRNA7CHRNB4 | |
| SCHEMBL1598674 | 0.76 | FPR3 (0.53) | HCRTR1HCRTR2OPRK1 | |
| SCHEMBL1598677 | 0.76 | FPR3 (0.53) | HCRTR1HCRTR2OPRK1 | |
| SCHEMBL17141620 | 0.75 | NPC1 (0.48) | — | |
| SCHEMBL10208455 | 0.74 | NPC1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |