Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825058 | 0.92 | NPSR1 (0.41) | SMOMEN1KMT2APOLBCCR8 | |
| SCHEMBL12825027 | 0.85 | SMO (0.43) | SMOMAPT | |
| SCHEMBL12825060 | 0.85 | SMO (0.43) | CYP2C19SMOMEN1KMT2AMAPT | |
| SCHEMBL10003951 | 0.84 | SMO (0.49) | CYP2D6CYP2C19LMNAGLAHSD17B10 | |
| SCHEMBL12825025 | 0.84 | SMO (0.48) | LMNAGLAHSD17B10CTDSP1SMO | |
| SCHEMBL12825061 | 0.84 | SMO (0.46) | SMO | |
| SCHEMBL12824727 | 0.84 | SMO (0.45) | SMOMEN1KMT2ACCR8MAPT | |
| SCHEMBL12825070 | 0.83 | NPSR1 (0.39) | MEN1KMT2ACCR8NPSR1 | |
| SCHEMBL12825026 | 0.83 | SMO (0.43) | SMOCCR8MAPT | |
| SCHEMBL12824722 | 0.81 | SMO (0.43) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |