Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 3/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825070 | 0.92 | NPSR1 (0.39) | NPSR1MEN1KMT2ACCR8KDM5A | |
| SCHEMBL12824860 | 0.92 | CYP2D6 (0.42) | NPSR1MEN1POLBKMT2ACCR8 | |
| SCHEMBL12824597 | 0.88 | NPSR1 (0.42) | NPSR1MEN1POLBKMT2ACCR8 | |
| SCHEMBL10003576 | 0.85 | SMO (0.46) | NPSR1MEN1POLBKMT2ACCR8 | |
| SCHEMBL12825028 | 0.84 | TSHR (0.41) | MEN1POLBKMT2ACCR8EPHX2 | |
| SCHEMBL12825027 | 0.80 | SMO (0.43) | SMOEPHX2 | |
| SCHEMBL12824625 | 0.80 | SMN1; SMN2 (0.42) | MEN1POLBKMT2ACCR8EPHX2 | |
| SCHEMBL12824626 | 0.80 | CNR1 (0.39) | EPHX2KDM5A | |
| SCHEMBL12825060 | 0.80 | SMO (0.43) | MEN1KMT2ASMOEPHX2 | |
| SCHEMBL12825025 | 0.79 | SMO (0.48) | NPSR1CCR8SMOEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |