Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499494 | 1.00 | SOD1 (0.32) | SOD1EP300NR3C1PGRNR3C2 | |
| SCHEMBL12821421 | 0.88 | SOD1 (0.34) | SOD1EP300NR3C1PGRNR3C2 | |
| SCHEMBL16499253 | 0.85 | SOD1 (0.32) | SOD1EP300 | |
| SCHEMBL16499551 | 0.78 | MEN1 (0.33) | SOD1 | |
| SCHEMBL12825604 | 0.78 | ACHE (0.37) | SOD1EP300PGR | |
| SCHEMBL12821396 | 0.75 | ACHE (0.35) | SOD1EP300PGRAR | |
| SCHEMBL16499584 | 0.75 | ACHE (0.35) | SOD1EP300PGRAR | |
| SCHEMBL16499573 | 0.74 | OPRM1 (0.45) | — | |
| SCHEMBL12825588 | 0.73 | ACHE (0.44) | SOD1EP300 | |
| SCHEMBL12825590 | 0.72 | EP300 (0.30) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |