Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836931 | 0.93 | ADRB2 (0.48) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL116252 | 0.90 | ADRB2 (0.50) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL12825634 | 0.89 | ADRB2 (0.46) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL12825622 | 0.88 | KDM4E (0.51) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL12825619 | 0.87 | ADRB2 (0.48) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL117111 | 0.87 | ADRB2 (0.49) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL116167 | 0.87 | ADRB2 (0.49) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL115801 | 0.85 | ADRB2 (0.49) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL116234 | 0.85 | ADRB2 (0.50) | ADRB2KCNH2ALDH1A1POLBOPRM1 | |
| SCHEMBL12836651 | 0.84 | ADRB2 (0.49) | ADRB2KCNH2ALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031740-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |