Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836934 | 0.92 | ALDH1A1 (0.51) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12825629 | 0.88 | ADRB2 (0.49) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL116181 | 0.88 | ALDH1A1 (0.52) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12825636 | 0.85 | ALDH1A1 (0.50) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL116169 | 0.84 | ALDH1A1 (0.56) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL116057 | 0.83 | ALDH1A1 (0.53) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL114575 | 0.82 | ALDH1A1 (0.54) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12836652 | 0.81 | ALDH1A1 (0.51) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12819497 | 0.81 | LMNA (0.54) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12836931 | 0.81 | ADRB2 (0.48) | KDM4EKCNH2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031740-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |