Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981480 | 0.79 | KMT2A (0.54) | GAAKMT2AALDH1A1HTTHSD17B10 | |
| SCHEMBL21281700 | 0.72 | HTT (0.44) | GAAKMT2AALDH1A1HTTPDE1A | |
| SCHEMBL12826269 | 0.69 | GAA (0.57) | GAAKMT2AALDH1A1HTTRAB9A | |
| SCHEMBL21721553 | 0.68 | CNR1 (0.33) | ALDH1A1HTTBRD9L3MBTL1PDE10A | |
| SCHEMBL12826267 | 0.68 | GAA (0.53) | GAAKMT2AALDH1A1HTTRAB9A | |
| SCHEMBL10366469 | 0.66 | GAA (0.50) | GAAKMT2AALDH1A1HTTRAB9A | |
| SCHEMBL25447709 | 0.65 | LMNA (0.43) | GAAKMT2AALDH1A1HSD17B10RAB9A | |
| Ethoxycarbonyl Group SCHEMBL28815733 | 0.65 | PDE10A (0.43) | GAAALDH1A1HTTHSD17B10PDE1A | |
| SCHEMBL14038250 | 0.64 | GAA (0.45) | GAAKMT2AALDH1A1HTTHSD17B10 | |
| SCHEMBL12497134 | 0.64 | GAA (0.45) | GAAKMT2AALDH1A1HTTPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028492-A2 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-03-10 | — | — | WO | disclosed |