Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | JAK2 | O60674 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | STAT1 | P42224 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129286 | 0.83 | NPC1 (0.51) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1463425 | 0.78 | RAB9A (1.00) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1463376 | 0.78 | RAB9A (0.76) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1462289 | 0.78 | JAK3 (1.00) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1463310 | 0.76 | JAK3 (0.80) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL12746080 | 0.76 | RAB9A (0.77) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1462349 | 0.75 | JAK3 (1.00) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1463421 | 0.75 | JAK3 (1.00) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1463316 | 0.75 | JAK3 (1.00) | RAB9ANPC1JAK2TP53STAT1 | |
| SCHEMBL1462316 | 0.75 | RAB9A (1.00) | RAB9ANPC1JAK2TP53STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071149-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071149-A1 | SELECTIVE KINASE INHIBITORS | JAK3, JAK1, JAK2 | RAB9A 1139/4885NPC1 3267/4885JAK2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.