Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262080 | 0.86 | RAB9A (0.71) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL30504811 | 0.85 | RAB9A (0.89) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL15293581 | 0.83 | RAB9A (0.58) | RAB9ANPC1PKMALDH1A1HTT | |
| SCHEMBL10031567 | 0.82 | MEN1 (0.58) | LMNAALDH1A1HTTNAMPTMEN1 | |
| SCHEMBL12447388 | 0.82 | LMNA (0.57) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL29602550 | 0.82 | RAB9A (0.65) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL49506 | 0.82 | RAB9A (0.65) | RAB9ANPC1PKMLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL5095381 | 0.80 | RAB9A (0.62) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL6630167 | 0.80 | RAB9A (0.79) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL1504253 | 0.79 | RAB9A (0.67) | RAB9ANPC1PKMLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915280-B2 | Compounds and their uses | EISAI INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-RE41150-E1 | Poly(adenosine 5'-diphospho-ribose) polymerase (PARP) inhibitors; compounds based on thieno(4,3,2-ef)(2)benzazepin-6-one | EISAI CORPORATION OF NORTH AMERICA (US) | 2010-02-23 | — | — | US | disclosed |
| EP-2080616-A1 | Planographic printing plate precursor | Fujifilm Corporation (JP) | 2009-07-22 | — | — | EP | disclosed |