Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NAMPT | P43490 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602550 | 1.00 | RAB9A (0.65) | RAB9ANPC1PKMLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL5095381 | 0.98 | RAB9A (0.62) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL6490312 | 0.90 | GAA (0.55) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL9262080 | 0.85 | RAB9A (0.71) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL30504811 | 0.83 | RAB9A (0.89) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL30051982 | 0.83 | MEN1 (0.77) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL9637653 | 0.83 | MEN1 (0.77) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL11036486 | 0.82 | ALDH1A1 (0.65) | RAB9ANPC1PKMLMNAALDH1A1 | |
| SCHEMBL12828408 | 0.82 | RAB9A (0.67) | RAB9ANPC1PKMLMNAHIF1A | |
| SCHEMBL11213715 | 0.82 | RAB9A (0.72) | RAB9ANPC1PKMLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707964-A | Preparation method of (8-bromoindolizine-3-yl) (3, 4, 5-trifluoro phenyl) ketone | 无锡科华生物科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-116478152-A | Small molecular marrow cell proliferation inhibitor and preparation method and application thereof | 复旦大学 | 2023-07-25 | — | — | CN | claimed |
| WO-2023088285-A1 | SMALL MOLECULE INHIBITOR AGAINST NASOPHARYNGEAL CARCINOMA, PREPARATION METHOD FOR COMPOUND AND APPLICATION THEREOF | 深圳湾实验室 | 2023-05-25 | — | — | WO | claimed |
| CN-115210339-A | Etching solution for titanium nitride and molybdenum conductive metal wires | 弗萨姆材料美国有限责任公司 | 2022-10-18 | — | — | CN | claimed |
| CN-107848974-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | claimed |
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-103958479-B | Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof | 赛诺菲 | 2017-06-13 | — | — | CN | claimed |
| CN-103012397-B | Pyrazolo (E)-3-(3-Acetyl-4-hydroxy-5-methoxy-phenyl)-N-(4-hydroxy-1-methyl-3-octyloxy-2-oxo-1,2-dihydro-quinolin-7-yl)-acrylamide, its preparation method and its therapeutic use | 赛诺菲 | 2017-03-01 | — | — | CN | claimed |
| CN-103687860-A | As P2X7Heterocyclic amide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2014-03-26 | — | — | CN | claimed |
| US-20130172562-A1 | PROCESS FOR THE PREPARATION OF A SINGLE ENANTIOMER OF 3-AMINOPIPERIDINE DIHYDROCHLORIDE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-07-04 | — | — | US | claimed |
| US-6436919-B1 | LOCAL ANESTHETICS THAT HAVE LONGER DURATION OF ACTION WHILE REDUCING UNDESIRED SIDE EFFECTS | THERAVANCE INC. | 2002-08-20 | — | — | US | claimed |
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | PHARMACIA & UPJOHN COMPANY | 2002-08-08 | — | — | US | claimed |
| WO-2002051983-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| EP-1216243-A1 | QUINAZOLINONES AND ANALOGUES AND THEIR USE AS LOCAL ANESTHETICS | Advanced Medicine, Inc. (US) | 2002-06-26 | — | — | EP | claimed |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2002-06-20 | — | — | US | claimed |
| WO-2002024701-A2 | SUBSTITUTED AZEPINO[4,5B)INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024700-A2 | SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| WO-2001025234-A1 | QUINAZOLINONES AND ANALOGUES AND THEIR USE AS LOCAL ANESTHETICS | ADVANCED MEDICINE, INC. (US) | 2001-04-12 | — | — | WO | claimed |
| US-5696282-A | CATALYTIC REACTION OF A HYDROGEN SULFIDE OR MERCAPTAN WITH UNSATURATED CARBONYL OR CYANO COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1997-12-09 | — | — | US | claimed |
| US-4124386-A | Color diffusion transfer receiving layer comprising polymeric quaternary n-heterocyclic mordant | FUJI PHOTO FILM CO., LTD. (JP) | 1978-11-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | HTR5A, HTR1A, HTR1E | RAB9A 698/4885NPC1 1345/4885PKM 3637/4885 |
| US-20130172562-A1 | PROCESS FOR THE PREPARATION OF A SINGLE ENANTIOMER OF 3-AMINOPIPERIDINE DIHYDROCHLORIDE | RAC3, RAC2, RAPGEF4 | RAB9A 45/4885NPC1 3781/4885PKM 2882/4885 |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | HTR5A, HTR1A, HTR4 | RAB9A 751/4885NPC1 1176/4885PKM 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.