SCHEMBL1282877

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2759558	0.90	RAB9A (0.71)	ABL1NPC1RAB9ASMN1; SMN2CYP1A2
	SCHEMBL2820972	0.88	RAB9A (0.69)	ABL1NPC1RAB9ASMN1; SMN2CYP1A2
	SCHEMBL2732073	0.87	RAB9A (0.66)	ABL1NPC1RAB9ASMN1; SMN2CYP1A2
	SCHEMBL2792432	0.86	ABL1 (0.64)	ABL1NPC1RAB9ASMN1; SMN2CYP1A2
	Potassium Ion SCHEMBL2790234	0.86	ABL1 (0.66)	ABL1PIK3CAPIK3CGNPC1RAB9A
	SCHEMBL6068271	0.85	ABL1 (0.65)	ABL1PIK3CAPIK3CGNPC1RAB9A
	SCHEMBL6067997	0.83	DYRK1A (0.71)	ABL1PIK3CAPIK3CGNPC1RAB9A
	SCHEMBL14189671	0.83	ABL1 (0.70)	ABL1PIK3CAPIK3CGNPC1RAB9A
	SCHEMBL4918595	0.83	NPC1 (1.00)	PIK3CAPIK3CGNPC1RAB9ASMN1; SMN2
	SCHEMBL2733651	0.82	RAB9A (0.70)	NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.