Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.71 |
| ▸ | NPC1 | O15118 | 11/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | CASP2 | P42575 | 1/20 | 0.69 |
| ▸ | ABL1 | P00519 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282877 | 0.90 | ABL1 (0.83) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL2820972 | 0.86 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL2732073 | 0.85 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL2792432 | 0.84 | ABL1 (0.64) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| Potassium Ion SCHEMBL2790234 | 0.84 | ABL1 (0.66) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL20543332 | 0.81 | CASP2 (1.00) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL12963106 | 0.81 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL4918595 | 0.81 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL2733651 | 0.81 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2TSHRCASP2 | |
| SCHEMBL213883 | 0.80 | GSK3B (0.78) | RAB9ANPC1SMN1; SMN2TSHRCASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | METHYLGENE INC. (CA) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | HDAC1, HDAC11, HDAC5 | RAB9A 3036/4885NPC1 1293/4885SMN1; SMN2 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.