Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486246 | 0.80 | TAS1R3 (0.65) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL12182474 | 0.78 | GAA (0.82) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL4201407 | 0.75 | TAS1R3 (1.00) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL179086 | 0.74 | SMN1; SMN2 (0.77) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL14424472 | 0.74 | RAB9A (0.66) | TAS1R3TAS1R1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28366072 | 0.73 | ALDH1A1 (0.74) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL29975649 | 0.73 | ALDH1A1 (0.74) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL5923977 | 0.73 | TAS1R3 (0.68) | LMNATAS1R3TAS1R1SMN1; SMN2MAPT | |
| SCHEMBL6991114 | 0.72 | ALDH1A1 (0.72) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL5385475 | 0.72 | ALDH1A1 (0.72) | LMNASMN1; SMN2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289888-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |