Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829325 | 0.81 | LMNA (0.42) | CA2CA1CA12ALDH1A1RECQL | |
| SCHEMBL1819324 | 0.79 | TSHR (0.48) | CA2CA1CA12ALDH1A1CYP3A4 | |
| SCHEMBL7098293 | 0.79 | SMN1; SMN2 (0.45) | CA2CA1CA12ALDH1A1HSD17B10 | |
| SCHEMBL13588724 | 0.76 | CA2 (0.57) | CA2CA1CA12ALDH1A1RECQL | |
| SCHEMBL9175160 | 0.72 | ALDH1A1 (0.61) | CA2CA1CA12ALDH1A1RECQL | |
| SCHEMBL35747 | 0.72 | ALDH1A1 (0.61) | CA2CA1CA12ALDH1A1RECQL | |
| Sulfuric Acid SCHEMBL16207785 | 0.71 | ALDH1A1 (0.81) | CA2CA1CA12ALDH1A1RECQL | |
| SCHEMBL19567317 | 0.71 | CA12 (0.55) | CA2CA1CA12ALDH1A1RECQL | |
| SCHEMBL13196224 | 0.70 | LMNA (0.38) | ALDH1A1RECQLHPGDTP53NPSR1 | |
| SCHEMBL13744645 | 0.70 | SNCA (0.43) | ALDH1A1HSD17B10HPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077375-A1 | Functionalized particles | HUNTSMAN TEXTILE EFFECTS (GERMANY) GMBH (DE) | 2011-03-31 | — | — | US | disclosed |