Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | P2RX3 | P56373 | 16/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 16/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12830820 | 0.88 | NR1I2 (0.47) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12830812 | 0.87 | P2RX3 (0.49) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12831023 | 0.86 | NR1I2 (0.46) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL1495440 | 0.85 | NR1I2 (0.61) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL1495392 | 0.81 | NR1I2 (0.57) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12757538 | 0.81 | NR1I2 (0.57) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12256367 | 0.81 | NR1I2 (0.56) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL1495603 | 0.81 | NR1I2 (0.56) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL1495600 | 0.81 | NR1I2 (0.56) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12831100 | 0.80 | P2RX3 (0.40) | NR1I2CYP2C9P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065681-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065681-A1 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | IL1B, ADORA2B, AVPR1B | NR1I2 461/4885CYP2C9 1604/4885P2RX3 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.