Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 4/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756756 | 0.94 | GLS (0.49) | GLSSCN3AMEN1KMT2ANFKB1 | |
| SCHEMBL12756745 | 0.89 | GLS (0.42) | GLSMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL12756753 | 0.87 | NFKB1 (0.43) | GLSMEN1KMT2ANFKB1NFKB2 | |
| SCHEMBL1954085 | 0.83 | ANO1 (0.53) | GLSMEN1KMT2AANO1NPC1 | |
| SCHEMBL1950210 | 0.77 | ANO1 (0.55) | GLSANO1 | |
| SCHEMBL12756741 | 0.75 | L3MBTL1 (0.56) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12756734 | 0.74 | NPY5R (0.39) | MEN1KMT2ANPC1HDAC3HDAC1 | |
| SCHEMBL12831284 | 0.73 | ANO1 (0.56) | ANO1NPC1HDAC1 | |
| SCHEMBL12831055 | 0.73 | NFKB1 (0.42) | GLSMEN1KMT2ANFKB1NFKB2 | |
| SCHEMBL12831001 | 0.73 | NFKB1 (0.42) | GLSMEN1KMT2ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |