Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ARNT | P27540 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15532063 | 0.81 | TSHR (0.53) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL24455476 | 0.81 | ALDH1A1 (0.60) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1848788 | 0.81 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL31123135 | 0.81 | ALDH1A1 (0.46) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1496397 | 0.80 | TP53 (0.42) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4085561 | 0.80 | LMNA (0.41) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL22325943 | 0.79 | LMNA (0.40) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27905696 | 0.77 | ALDH1A1 (0.41) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11789633 | 0.77 | ALDH1A1 (0.41) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28261052 | 0.77 | ARNT (0.43) | KMT2ALMNASMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |