Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | CMA1 | P23946 | 5/20 | 0.35 |
| ▸ | CTRC | Q99895 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6124837 | 0.93 | F2 (0.40) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL12831733 | 0.91 | F2 (0.38) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL13435877 | 0.88 | F2 (0.43) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL13435882 | 0.87 | F2 (0.40) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL13563948 | 0.87 | ITGB3 (0.40) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL12831734 | 0.84 | DPP4 (0.33) | F2 | |
| SCHEMBL10166392 | 0.83 | HDAC1 (0.35) | F2PRSS1ITGB3ITGA2B | |
| SCHEMBL6385317 | 0.83 | F2 (0.40) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL12831782 | 0.82 | ITGB3 (0.40) | F2PRSS1ITGB3ITGA2BCMA1 | |
| SCHEMBL12831634 | 0.82 | F2 (0.39) | F2PRSS1ITGB3ITGA2BCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |