Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.30 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071454 | 0.93 | DPP4 (0.33) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL12831724 | 0.84 | F2 (0.39) | F2 | |
| SCHEMBL12831740 | 0.80 | OPRM1 (0.34) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL6124837 | 0.78 | F2 (0.40) | F2 | |
| SCHEMBL13071463 | 0.75 | DPP4 (0.39) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL13071458 | 0.75 | DPP8 (0.38) | DPP4DPP8OPRM1F2 | |
| SCHEMBL12831733 | 0.75 | F2 (0.38) | F2 | |
| SCHEMBL13071561 | 0.75 | DPP4 (0.39) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL13071900 | 0.75 | TACR1 (0.36) | F2 | |
| SCHEMBL13711252 | 0.72 | AGTR2 (0.39) | DPP4DPP7DPP8DPP9OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |