Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495652 | 0.78 | TSHR (0.43) | KMT2AALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL14161087 | 0.75 | ALDH1A1 (0.48) | KMT2AALDH1A1KDM4EASAH1TSHR | |
| SCHEMBL24309082 | 0.73 | POLB (0.37) | KMT2AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL21090873 | 0.73 | POLB (0.47) | KMT2AALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL20442126 | 0.70 | KDM4E (0.40) | KMT2AALDH1A1KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL13880407 | 0.70 | ALDH1A1 (0.49) | KMT2AALDH1A1KDM4EASAH1TSHR | |
| SCHEMBL21698289 | 0.67 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EASAH1TSHR | |
| SCHEMBL179064 | 0.66 | SMN1; SMN2 (0.61) | KMT2AALDH1A1KDM4ETSHRL3MBTL1 | |
| SCHEMBL13534479 | 0.66 | MAPK1 (0.50) | KMT2AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL20083353 | 0.65 | HSD17B10 (0.44) | KMT2AALDH1A1KDM4ETSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |