Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 2/20 | 0.31 |
| ▸ | ATP4B | P51164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421149 | 0.94 | MEN1 (0.32) | MEN1GAAKMT2AATP4AATP4B | |
| SCHEMBL445551 | 0.93 | MEN1 (0.32) | MEN1GAAKMT2AATP4AATP4B | |
| SCHEMBL445552 | 0.93 | MEN1 (0.32) | MEN1GAAKMT2AATP4AATP4B | |
| SCHEMBL12287233 | 0.89 | ATP4A (0.33) | ATP4AATP4B | |
| SCHEMBL419870 | 0.86 | HSP90AA1 (0.32) | — | |
| SCHEMBL14293305 | 0.84 | — | — | |
| SCHEMBL13639211 | 0.83 | MAPT (0.33) | MEN1KMT2AATP4AATP4B | |
| SCHEMBL421457 | 0.83 | HSP90AA1 (0.32) | MEN1GAAKMT2A | |
| SCHEMBL12203088 | 0.83 | HSP90AA1 (0.32) | MEN1GAAKMT2A | |
| SCHEMBL421429 | 0.82 | GABRA1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298748-A2 | Triazole compounds that modulate HSP90 activity | Synta Pharmaceuticals Corp. (US) | 2011-03-23 | — | — | EP | disclosed |