Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106150 | 0.86 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL137754 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL27646050 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL29066927 | 0.79 | CYP3A4 (0.43) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL18332194 | 0.75 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL31700561 | 0.75 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL31729102 | 0.75 | CD44 (0.41) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL2002230 | 0.75 | CD44 (0.41) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL9495198 | 0.72 | CASP1 (0.48) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL360400 | 0.72 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298770-A1 | Heterocyclic compounds as TrkA modulators | ChemBridge Corporation (US) | 2011-03-23 | — | — | EP | disclosed |