Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179999 | 0.86 | LIPE (0.67) | LIPEMEN1POLBKMT2AKDM4E | |
| SCHEMBL31596882 | 0.81 | LIPE (0.58) | LIPEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7550305 | 0.79 | LIPE (1.00) | LIPEMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL27709492 | 0.79 | CYP1A2 (0.58) | CYP1A2CYP2D6MEN1POLBKMT2A | |
| SCHEMBL8030549 | 0.79 | LIPE (0.71) | LIPEMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL640619 | 0.78 | CYP1A2 (0.76) | CYP1A2CYP2D6MEN1POLBKMT2A | |
| SCHEMBL11844842 | 0.78 | MEN1 (0.68) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL603756 | 0.77 | LIPE (0.71) | LIPEMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3888640 | 0.77 | MAPT (0.68) | CYP1A2MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL17373926 | 0.76 | MGLL (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298292-A2 | Kinase inhibitors for treating cancers | Agennix USA Inc. (US) | 2011-03-23 | — | — | EP | disclosed |