Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 4/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12223404 | 0.78 | FEN1 (0.36) | FEN1ALOX5APNOTUMWDR5STS | |
| SCHEMBL19466332 | 0.75 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL24203140 | 0.73 | FEN1 (0.33) | FEN1ALOX5APNOTUMWDR5STS | |
| SCHEMBL25981340 | 0.72 | NOTUM (0.40) | FEN1ALOX5APNOTUMADRA2AADRA2B | |
| SCHEMBL11939197 | 0.72 | FEN1 (0.39) | FEN1ALOX5APNOTUMWDR5STS | |
| SCHEMBL28204231 | 0.71 | NUDT1 (0.41) | FEN1ALOX5AP | |
| SCHEMBL12662767 | 0.70 | ESR2 (0.44) | FEN1ALOX5APNOTUMWDR5STS | |
| SCHEMBL29234124 | 0.70 | FEN1 (0.32) | FEN1ALOX5APNOTUMWDR5 | |
| SCHEMBL24753238 | 0.70 | RPS6KA3 (0.41) | FEN1ALOX5APSTSCYP19A1 | |
| SCHEMBL15725306 | 0.70 | ESR2 (0.44) | FEN1ALOX5APNOTUMWDR5STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731493-B1 | BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORP (JP) | 2011-03-23 | — | — | EP | disclosed |