Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12346203 | 0.88 | NAAA (0.50) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL16248615 | 0.88 | ALDH1A1 (0.57) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL26733411 | 0.88 | ALDH1A1 (0.52) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL23471810 | 0.86 | ALDH1A1 (0.50) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL12346208 | 0.85 | NAAA (0.47) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL4904632 | 0.84 | CASP2 (0.62) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL24826063 | 0.84 | CNR1 (0.52) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL19161331 | 0.83 | KMT2A (0.43) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL18313728 | 0.83 | ALDH1A1 (0.52) | NAAAALDH1A1LMNAPKMCNR1 | |
| SCHEMBL16390142 | 0.83 | CNR1 (0.49) | NAAAALDH1A1LMNAPKMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298356-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS, INC. (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2258400-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | ELAN PHARMACEUTICALS, INC. (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258399-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | Elan Pharmaceuticals Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009075806-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |