Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835506 | 0.86 | CYP3A4 (0.52) | CYP19A1MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL12835309 | 0.86 | TNKS (0.52) | CYP19A1MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL12835502 | 0.85 | CYP19A1 (0.47) | CYP19A1MAPTCALM1FTONPC1 | |
| Mitoflaxone SCHEMBL106705 | 0.84 | CYP1A2 (0.62) | CYP19A1MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL12835503 | 0.82 | CYP1A2 (0.60) | CYP19A1MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL12835338 | 0.81 | TDP1 (0.57) | CYP19A1MAPTNPC1RAB9APKM | |
| SCHEMBL12835534 | 0.76 | ABCB1 (0.55) | CYP19A1MAPTCALM1FTOPKM | |
| SCHEMBL12835306 | 0.76 | CYP19A1 (0.67) | CYP19A1MAPTCALM1FTOPKM | |
| SCHEMBL11202458 | 0.75 | ALOX5 (0.45) | MAPTPKMCYP3A4HPGDKDM4E | |
| SCHEMBL7085634 | 0.75 | CYP2D6 (0.53) | CYP19A1MAPTCYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |