Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | TERT | O14746 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380070 | 0.83 | HPGD (0.65) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| 7,8-Dihydroxyflavone SCHEMBL29374601 | 0.80 | TERT (1.00) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| 7,8-Dihydroxyflavone SCHEMBL419316 | 0.80 | TERT (1.00) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| 7,8-Dihydroxyflavone SCHEMBL21852713 | 0.79 | TERT (0.97) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| Mitoflaxone SCHEMBL106705 | 0.78 | CYP1A2 (0.62) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL28461887 | 0.78 | CYP19A1 (0.74) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL31632309 | 0.78 | CYP19A1 (0.74) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL31632435 | 0.78 | CYP19A1 (0.74) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL28604212 | 0.77 | CYP19A1 (0.53) | CYP19A1MAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL21682943 | 0.76 | CYP19A1 (0.67) | CYP19A1MAPTHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |