Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | TGM2 | P21980 | 3/20 | 0.42 |
| ▸ | TGM1 | P22735 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836627 | 1.00 | ELANE (0.47) | ELANEF2CTSGALDH1A1GAA | |
| SCHEMBL26782867 | 0.91 | ALDH1A1 (0.44) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL25907337 | 0.89 | ALDH1A1 (0.47) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL25907342 | 0.86 | ALDH1A1 (0.45) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL12836415 | 0.85 | ABCB1 (0.46) | ELANEF2CTSGABCB1F13A1 | |
| SCHEMBL12836416 | 0.85 | ABCB1 (0.46) | ELANEF2CTSGABCB1F13A1 | |
| SCHEMBL17228509 | 0.85 | ALDH1A1 (0.43) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL25907341 | 0.85 | CTSK (0.50) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL31321288 | 0.84 | CPB1 (0.47) | ALDH1A1GAACPB1CTSLCTSB | |
| SCHEMBL140565 | 0.83 | SYK (0.46) | ALDH1A1GAACPB1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031745-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |