Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469269 | 0.83 | LMNA (0.49) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL10672670 | 0.77 | LMNA (0.46) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL11715638 | 0.77 | LMNA (0.43) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL4172164 | 0.77 | LMNA (0.74) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL7578567 | 0.74 | KDM4E (0.48) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL26979235 | 0.73 | KMT2A (0.37) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL18306040 | 0.73 | LMNA (0.41) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL18305929 | 0.73 | TSHR (0.42) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL7841138 | 0.72 | LMNA (0.49) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL18313140 | 0.71 | SMN1; SMN2 (0.42) | LMNAMEN1KMT2ATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028979-A1 | STABLE SNS-595 COMPOSITIONS AND METHODS OF PREPARATION | SUNESIS PHARMACEUTICALS, INC. (US) | 2011-03-10 | — | — | WO | disclosed |