Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068308 | 0.93 | AKR1B1 (0.37) | ROCK2BCHEACHEIKBKBALDH1A1 | |
| SCHEMBL12840229 | 0.92 | NPC1 (0.35) | SMN1; SMN2NPC1RAB9AROCK2KCNQ2 | |
| SCHEMBL13067757 | 0.92 | ENPP2 (0.38) | SMN1; SMN2NPC1RAB9AROCK2IKBKB | |
| SCHEMBL12840235 | 0.92 | ALDH1A1 (0.37) | NPC1RAB9AROCK2ALDH1A1MAPK14 | |
| SCHEMBL12840239 | 0.92 | TSHR (0.39) | SMN1; SMN2NPC1RAB9AKCNQ2IKBKB | |
| SCHEMBL13067900 | 0.89 | CDK2 (0.35) | SMN1; SMN2ROCK2BCHEACHEIKBKB | |
| SCHEMBL12840237 | 0.89 | MEN1 (0.41) | SMN1; SMN2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL12840129 | 0.88 | NLRP3 (0.40) | SMN1; SMN2NPC1RAB9AROCK2KCNQ2 | |
| SCHEMBL12840244 | 0.88 | IKBKB (0.43) | SMN1; SMN2RAB9AROCK2KCNQ2IKBKB | |
| SCHEMBL12840152 | 0.88 | NLRP3 (0.39) | SMN1; SMN2NPC1RAB9AIKBKBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110070656-A1 | Fluorescent Proteins | JNC CORPORATION (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110070656-A1 | Fluorescent Proteins | CACYBP, CHLSN, LCP2 | SMN1; SMN2 4784/4885NPC1 2936/4885RAB9A 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.