SCHEMBL12840353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12838906	0.93	RIOK2 (0.51)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12840507	0.92	RIOK2 (0.50)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12839176	0.92	RIOK2 (0.50)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12839947	0.92	RIOK2 (0.49)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12838965	0.91	RIOK2 (0.53)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12838995	0.89	RIOK2 (0.49)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12840367	0.89	TMIGD3 (0.52)	MEN1KMT2AWNT3A
	SCHEMBL12840375	0.89	RIOK2 (0.47)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12839936	0.88	RIOK2 (0.48)	RIOK2GSK3AMAPK10MAPK8HIPK1
	SCHEMBL12839010	0.87	WNT3A (0.42)	RIOK2MEN1KMT2AWNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.